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AI Native Vertical SaaS Building Framework

GREG ISENBERG · Feb 25, 2026

how to build an ai native vertical saas in the claude cowork era:

  1. pick a sub-niche inside a large, profitable market
  2. map one recurring workflow that drives revenue or saves time
  3. write the workflow step-by-step like you're training an intern
  4. separate mechanical steps from judgment calls
  5. connect claude to the actual stack: crm, sheets, inbox, slides, contracts
  6. remove exports and copy-paste from the process
  7. collapse raw data → reasoning → finished output into one session
  8. store every output so context compounds over time
  9. turn your best prompts into named, reusable commands
  10. build memory around the niche (not generic instructions)
  11. package the result as a finished outcome
  12. price per report, per memo, per meeting, per deliverable
  13. publish the workflow collapsing in real time for distribution
  14. use organic traction as signal before running paid ads
  15. expand into adjacent workflows inside the same vertical
  16. layer governance and approvals where required
  17. become the default operating layer for that sub niche
  18. repeat the model in the next vertical once memory and distribution compound

Good times: claude can now sit inside real enterprise tools:

  • google workspace
  • excel + powerpoint
  • crm systems
  • prospecting tools like apollo + clay
  • traffic data like similarweb
  • contracts via docusign

That means the model sees the full workflow. The opportunity for you: find a niche. Collapse a workflow. Package the outcome. Own the memory. Expand from there. That's how ai native saas gets built now. It's a wonderful time to be building.