concepts · tweet · 1 min
AI Native Vertical SaaS Building Framework
GREG ISENBERG · Feb 25, 2026
how to build an ai native vertical saas in the claude cowork era:
- pick a sub-niche inside a large, profitable market
- map one recurring workflow that drives revenue or saves time
- write the workflow step-by-step like you're training an intern
- separate mechanical steps from judgment calls
- connect claude to the actual stack: crm, sheets, inbox, slides, contracts
- remove exports and copy-paste from the process
- collapse raw data → reasoning → finished output into one session
- store every output so context compounds over time
- turn your best prompts into named, reusable commands
- build memory around the niche (not generic instructions)
- package the result as a finished outcome
- price per report, per memo, per meeting, per deliverable
- publish the workflow collapsing in real time for distribution
- use organic traction as signal before running paid ads
- expand into adjacent workflows inside the same vertical
- layer governance and approvals where required
- become the default operating layer for that sub niche
- repeat the model in the next vertical once memory and distribution compound
Good times: claude can now sit inside real enterprise tools:
- google workspace
- excel + powerpoint
- crm systems
- prospecting tools like apollo + clay
- traffic data like similarweb
- contracts via docusign
That means the model sees the full workflow. The opportunity for you: find a niche. Collapse a workflow. Package the outcome. Own the memory. Expand from there. That's how ai native saas gets built now. It's a wonderful time to be building.